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Again, there are three possible choices for the second B ligand: at position 2 or 3 on the same triangular face, position 4 (on the other triangular face but adjacent to 1), or position 5 or 6 (on the other triangular face but not adjacent to 1)

As additional research becomes available, recommendations related to the use of glucose-lowering agents to optimize glycemic, cardiovascular, and renal outcomes will undoubtedly continue to evolve and inform patient-centered diabetes care

Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C

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Zhou B, Zhang J-y, Liu X-s, Chen H-z, Ai Y-l, Cheng K, et al